Protection of Quiescence and Longevity of IgG Memory B Cells by Mitochondrial Autophagy

Abstract excerpt

Abstract The development of long-lived immune memory cells against pathogens is critical for the success of vaccines to establish protection against future infections. However, the mechanisms governing the long-term survival of immune memory cells remain to be elucidated. In this article, we show that the maintenance mitochondrial homeostasis by autophagy is critical for restricting metabolic functions to protect...

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