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Article

Demethylation at enhancer upregulates MCM2 and NUP37 expression predicting poor survival in hepatocellular carcinoma patients

29 Jan 2022

Abstract excerpt

BACKGROUND: Identification of novel biomarker is important for development of molecular-targeted therapy agents for patients with hepatocellular carcinoma (HCC). This study aims to identify potential prognostic biomarkers and investigate epigenetic mechanism of HCC development. METHODS: Public bulk-RNA seq datasets and proteomic dataset were screened for identification of potential prognostic biomarkers for HCC...

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Share to Cancer, Hypoxia, and Metabolism
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PMID: 35093119
DOI: 10.1186/s12967-022-03249-2

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