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Article

Systemic lupus erythematosus patients contain B‐cell receptor repertoires sensitive to immunosuppressive drugs

29 Jan 2022

Abstract excerpt

Immune repertoire (IR) during treatment may be a surrogate biomarker for disease response. Changes of the IR in systemic lupus erythematosus patients in response to immunosuppressive drugs were identified in ten SLE patients. Patients provided peripheral blood mononuclear cells at two time points for sequencing. They were divided into sensitive and nonsensitive groups by their clinical responses to...

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PMID: 35092307
DOI: 10.1002/eji.202149596

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