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Article

The multifaceted role of ferroptosis in liver disease

24 Jan 2022

Abstract excerpt

Ferroptosis is an iron-dependent form of non-apoptotic cell death characterized by excessive lipid peroxidation and associated with a plethora of pathological conditions in the liver. Emerging evidence supports the notion that dysregulated metabolic pathways and impaired iron homeostasis play a role in the progression of liver disease via ferroptosis. Although the molecular mechanisms by which ferroptosis causes...

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PMID: 35075250
DOI: 10.1038/s41418-022-00941-0

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