Article
Contraceptive use and the risk of ovarian cancer among women with a BRCA1 or BRCA2 mutation.
Gynecologic oncology - 1 Mar 2022
Xia Yue Yin, Gronwald Jacek, Karlan Beth, Lubinski Jan, McCuaig Jeanna M, Brooks Jennifer, Moller Pal, Eisen Andrea, Sun Sophie, Senter Leigha, Bordeleau Louise, Neuhausen Susan L, Singer Christian F, Tung Nadine, Foulkes William D, Sun Ping, Narod Steven A, Kotsopoulos Joanne
Abstract excerpt
Background BRCA1 and BRCA2 (BRCA) mutation carriers face a high lifetime risk of developing ovarian cancer. Oral contraceptives are protective in this population; however, the impact of other types of contraception (e.g. intrauterine devices, implants, injections) is unknown. We undertook a matched case-control study to evaluate the relationship between type of contraception and risk of ovarian cancer among women...
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