Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

BSG (CD147) Serum Level and Genetic Variants Are Associated with Overall Survival in Acute Myeloid Leukaemia

10 Jan 2022

Abstract excerpt

Basigin (BSG, CD147) is a multifunctional protein involved in cancer cell survival, mostly by controlling lactate transport through its interaction with monocarboxylate transporters (MCTs) such as MCT1. Previous studies have found that single nucleotide polymorphisms (SNPs) in the gene coding for BSG and MCT1, as well as levels of the soluble form of BSG (sBSG), are potential biomarkers in various diseases. The...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Galectins and Cancer Biology
Share to Signaling Pathways in Disease

Source

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Identifiers

PMID: 35054026
DOI: 10.3390/jcm11020332

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 11 closest

BSG (CD147) Serum Level and Genetic Variants Are Associated with Overall Survival in Acute Myeloid LeukaemiaPMID 35054026Read ↗

Metabolic function and Therapeutic Potential of CD147 for Hematological Malignancies: An OverviewSemantic proximity Read ↗

Basigin (CD147): a multifunctional transmembrane protein involved in reproduction, neural function, inflammation and tumor invasion.Semantic proximity Read ↗

High expression of SLC38A1 predicts poor prognosis in patients with de novo acute myeloid leukemiaSemantic proximity Read ↗

BCAT1 restricts αKG levels in AML stem cells leading to IDHmut-like DNA hypermethylation.Semantic proximity Read ↗

Role of Human Monocarboxylate Transporter 1 (hMCT1) and 4 (hMCT4) in Tumor Cells and the Tumor MicroenvironmentSemantic proximity Read ↗

Anti-Tumor Effects of BDH1 in Acute Myeloid LeukemiaSemantic proximity Read ↗

Co-expression of monocarboxylate transporter 1 (MCT1) and its chaperone (CD147) is associated with low survival in patients with gastrointestinal stromal tumors (GISTs).Semantic proximity Read ↗

Knock out of the BASIGIN/CD147 chaperone of lactate/H+ symporters disproves its pro-tumour actionviaextracellular matrix metalloproteases (MMPs) inductionSemantic proximity Read ↗

In Vitro and In Vivo Characterization of MCT1 Inhibitor AZD3965 Confirms Preclinical Safety Compatible with Breast Cancer TreatmentSemantic proximity Read ↗

herg1b expression as a potential specific marker in pediatric acute myeloid leukemia patients with HERG 897K/K genotype.Semantic proximity Read ↗

Large granular lymphocyte leukemia serum and corresponding hematological parameters reveal unique cytokine and sphingolipid biomarkers and associations with STAT3 mutations.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.