Article
Genotype Score for Iron Status Is Associated with Muscle Fiber Composition in Women.
Genes - 21 Dec 2021
Takaragawa Mizuki, Tobina Takuro, Shiose Keisuke, Kakigi Ryo, Tsuzuki Takamasa, Ichinoseki-Sekine Noriko, Kumagai Hiroshi, Zempo Hirofumi, Miyamoto-Mikami Eri, Kobayashi Hiroyuki, Naito Hisashi, Fuku Noriyuki
Abstract excerpt
Human muscle fiber composition is heterogeneous and mainly determined by genetic factors. A previous study reported that experimentally induced iron deficiency in rats increases the proportion of fast-twitch muscle fibers. Iron status has been reported to be affected by genetic factors. As the TMPRSS6 rs855791 T/C and HFE rs1799945 C/G polymorphisms are strongly associated with iron status in humans, we...
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