Article
The association of HFE gene H63D polymorphism with endurance athlete status and aerobic capacity: novel findings and a meta-analysis.
European journal of applied physiology - 1 Mar 2020
Semenova Ekaterina A, Miyamoto-Mikami Eri, Akimov Egor B, Al-Khelaifi Fatima, Murakami Haruka, Zempo Hirofumi, Kostryukova Elena S, Kulemin Nikolay A, Larin Andrey K, Borisov Oleg V, Miyachi Motohiko, Popov Daniil V, Boulygina Eugenia A, Takaragawa Mizuki, Kumagai Hiroshi, Naito Hisashi, Pushkarev Vladimir P, Dyatlov Dmitry A, Lekontsev Eugene V, Pushkareva Yuliya E, Andryushchenko Liliya B, Elrayess Mohamed A, Generozov Edward V, Fuku Noriyuki, Ahmetov Ildus I
Abstract excerpt
PURPOSE: Iron is an important component of the oxygen-binding proteins and may be critical to optimal athletic performance. Previous studies have suggested that the G allele of C/G rare variant (rs1799945), which causes H63D amino acid replacement, in the HFE is associated with elevated iron indexes and may give some advantage in endurance-oriented sports. The aim of the present study was to investigate the...
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