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HFE Genotype and Endurance Performance in Competitive Male Athletes.

Medicine and science in sports and exercise - 1 Jul 2021

Thakkar Drishti, Sicova Marc, Guest Nanci S, Garcia-Bailo Bibiana, El-Sohemy Ahmed

Abstract excerpt

INTRODUCTION: Hereditary hemochromatosis can cause individuals to absorb too much iron from their diet. Higher tissue iron content, below the threshold of toxicity, may enhance oxygen carrying capacity and offer a competitive advantage. Single nucleotide polymorphisms (SNP) in the homeostatic iron regulator (HFE) gene have been shown to modify iron metabolism and can be used to predict an individual's risk of...

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PMID: 33433155
DOI: 10.1249/MSS.0000000000002595

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026.

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