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Article

An active site at work - the role of key residues in C. diphteriae coproheme decarboxylase.

Journal of inorganic biochemistry - 1 Apr 2022

Sebastiani Federico, Risorti Riccardo, Niccoli Chiara, Michlits Hanna, Becucci Maurizio, Hofbauer Stefan, Smulevich Giulietta

Abstract excerpt

Coproheme decarboxylases (ChdCs) are utilized by monoderm bacteria to produce heme b by a stepwise oxidative decarboxylation of the 2- and 4-propionate groups of iron coproporphyrin III (coproheme) to vinyl groups. This work compares the effect of hemin reconstitution versus the hydrogen peroxide-mediated conversion of coproheme to heme b in the actinobacterial ChdC from Corynebacterium diphtheriae (CdChdC) and...

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Identifiers

PMID: 35051755
DOI: 10.1016/j.jinorgbio.2022.111718

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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