Article
Melanoma with genetic alterations beyond the BRAFV600 mutation: management and new insights.
Current opinion in oncology - 1 Mar 2022
Awada Gil, Neyns Bart
Abstract excerpt
PURPOSE OF REVIEW: Molecular-targeted therapy with BRAF-/MEK-inhibitors has shown impressive activity in patients with advanced BRAFV600 mutant melanoma. In this review, we aim to summarize recent data and possible future therapeutic strategies involving small-molecule molecular-targeted therapies for advanced BRAFV600 wild-type melanoma. RECENT FINDINGS: In patients with NRASQ61 mutant melanoma, downstream...
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