Article
Clinical utility of plasma ctDNA sequencing in metastatic urothelial cancer.
European journal of cancer (Oxford, England : 1990) - 1 Dec 2023
Helal Clara, Pobel Cédric, Bayle Arnaud, Vasseur Damien, Nicotra Claudio, Blanc-Durand Félix, Naoun Natacha, Bernard-Tessier Alice, Patrikidou Anna, Colomba Emeline, Flippot Ronan, Fuerea Alina, Auger Nathalie, Ngo Camus Maud, Besse Benjamin, Lacroix Ludovic, Rouleau Etienne, Ponce Santiago, Italiano Antoine, Loriot Yohann
Abstract excerpt
BACKGROUND: Genomic stratification may help improve the management of patients with metastatic urothelial cancer (mUC), given the recent identification of targetable alterations. However, the collection of tissue samples remains challenging. Here, we assessed the clinical utility of plasma circulating tumour DNA (ctDNA) sequencing in these patients. METHODS: Patients with mUC were prospectively enroled in the...
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