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Article

Trophectoderm formation: regulation of morphogenesis and gene expressions by RHO, ROCK, cell polarity, and HIPPO signaling

28 Jul 2022

Abstract excerpt

In brief: Trophectoderm is the first tissue to differentiate in the early mammalian embryo and is essential for hatching, implantation, and placentation. This review article discusses the roles of Ras homolog family members (RHO) and RHO-associated coiled-coil containing protein kinases (ROCK) in the molecular and cellular regulation of trophectoderm formation. Abstract: The trophectoderm (TE) is the first tissue...

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PMID: 35900353
DOI: 10.1530/rep-21-0478

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