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Article

The UGT2A1/UGT2A2 locus is associated with COVID-19-related loss of smell or taste.

Nature genetics - 1 Feb 2022

Shelton Janie F, Shastri Anjali J, Fletez-Brant Kipper, Aslibekyan Stella, Auton Adam

Abstract excerpt

Using online surveys, we collected data regarding COVID-19-related loss of smell or taste from 69,841 individuals. We performed a multi-ancestry genome-wide association study and identified a genome-wide significant locus in the vicinity of the UGT2A1 and UGT2A2 genes. Both genes are expressed in the olfactory epithelium and play a role in metabolizing odorants. These findings provide a genetic link to the...

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PMID: 35039640
DOI: 10.1038/s41588-021-00986-w

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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