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Article

Associations of genetic variation in E3 SUMO-protein ligase CBX4 with noise-induced hearing loss.

Human molecular genetics - 7 Jul 2022

Wang Boshen, Wan Liu, Sun Peng, Zhang Ludi, Han Lei, Zhang Hengdong, Zhang Juan, Pu Yuepu, Zhu Baoli

Abstract excerpt

Noise-induced hearing loss (NIHL) is a multifactorial disease caused by environmental, genetic and epigenetic variables. SUMOylation is a post-translational modification that regulates biological processes. The objective of this study was to determine the link between genetic variation in the chromobox 4 (CBX4) and the risk of NIHL. This study applied a case-control design with 588 cases and 582 controls, and the...

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Identifiers

PMID: 35038734
DOI: 10.1093/hmg/ddac006

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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