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Functional genomics analysis identifies T and NK cell activation as a driver of epigenetic clock progression

14 Jan 2022

Abstract excerpt

BACKGROUND: Epigenetic clocks use DNA methylation (DNAm) levels of specific sets of CpG dinucleotides to accurately predict individual chronological age. A popular application of these clocks is to explore whether the deviation of predicted age from chronological age is associated with disease phenotypes, where this deviation is interpreted as a potential biomarker of biological age. This wide application,...

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Share to Epigenetics and DNA Methylation
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PMID: 35031073
DOI: 10.1186/s13059-021-02585-8

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