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Article

Inflammatory level under different p53 mutation status and the regulation role of curcumin in tumor microenvironment.

Immunobiology - 1 Mar 2022

Xu Liping, Xie Xiaoli, Li Xinbo, Duan Wenfang, Qiu Lei, Liu Huan, Luo Ying

Abstract excerpt

The inflammation is tightly associated with tumor development, promoting or inhibiting tumorigenesis. And mutant p53 is speculated to promote inflammation and tumorigenesis. The tumor associated macrophages are usually educated to present the anti-inflammatory profile to tune down antitumor immunity. However, the impact of p53 mutants on macrophages is not clear. Here, we compared the basal inflammatory level and...

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Identifiers

PMID: 35030341
DOI: 10.1016/j.imbio.2022.152177

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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