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Article

A human stem cell resource to decipher the biochemical and cellular basis of neurodevelopmental defects in Lowe syndrome.

Biology open - 15 Jan 2022

Akhtar Bilal M, Bhatia Priyanka, Acharya Shubhra, Sharma Sanjeev, Sharma Yojet, Bhuvanendran Nair Suseela Devi Aswathy, Ganapathy Kavina, Vasudevan Anil, Raghu Padinjat

Abstract excerpt

Human brain development is a complex process where multiple cellular and developmental events are coordinated to generate normal structure and function. Alteration in any of these events can impact brain development, manifesting clinically as neurodevelopmental disorders. Human genetic disorders of lipid metabolism often present with features of altered brain function. Lowe syndrome (LS) is an X-linked recessive...

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Identifiers

PMID: 35023542
DOI: 10.1242/bio.059066
PMCID: PMC8822356

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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