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Article

BRCA1 Variant Assessment Using a Simple Analytic Assay.

The journal of applied laboratory medicine - 4 May 2022

Kim Daniel M, Feilotter Harriet E, Davey Scott K

Abstract excerpt

BACKGROUND: We previously developed a biological assay to accurately predict BRCA1 (BRCA1 DNA repair associated) mutation status, based on gene expression profiles of Epstein-Barr virus-transformed lymphoblastoid cell lines. The original work was done using whole genome expression microarrays, and nearest shrunken centroids analysis. While these approaches are appropriate for model building, they are difficult to...

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PMID: 35021209
DOI: 10.1093/jalm/jfab163

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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