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Article

Covariation of viral recombination with single nucleotide variants during virus evolution revealed by CoVaMa.

Nucleic acids research - 22 Apr 2022

Wang Shiyi, Sotcheff Stephanea L, Gallardo Christian M, Jaworski Elizabeth, Torbett Bruce E, Routh Andrew L

Abstract excerpt

Adaptation of viruses to their environments occurs through the acquisition of both novel single-nucleotide variants (SNV) and recombination events including insertions, deletions, and duplications. The co-occurrence of SNVs in individual viral genomes during their evolution has been well-described. However, unlike covariation of SNVs, studying the correlation between recombination events with each other or with...

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PMID: 35018461
DOI: 10.1093/nar/gkab1259
PMCID: PMC9023271

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