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Article

Virus-derived variation in diverse human genomes.

PLoS genetics - 1 Apr 2021

Kojima Shohei, Kamada Anselmo Jiro, Parrish Nicholas F

Abstract excerpt

Acquisition of genetic material from viruses by their hosts can generate inter-host structural genome variation. We developed computational tools enabling us to study virus-derived structural variants (SVs) in population-scale whole genome sequencing (WGS) datasets and applied them to 3,332 humans. Although SVs had already been cataloged in these subjects, we found previously-overlooked virus-derived SVs. We...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 33901175
DOI: 10.1371/journal.pgen.1009324
PMCID: PMC8101998

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