Article
The amino-terminal domain of TRPV4 channel is involved in its trafficking to the nucleus.
Biochemical and biophysical research communications - 12 Feb 2022
Méndez-Gómez Susana, Espadas-Álvarez Heidi, Ramírez-Rodríguez Ivette, Domínguez-Malfavón Lilianha, García-Villegas Refugio
Abstract excerpt
Transient Receptor Potential Vanilloid 4 (TRPV4) ion channel is a sensor for multiple physical and chemical stimuli of ubiquitous expression that participates in various functions either in differentiated tissues or during differentiation. We recently demonstrated the nuclear localization of the full-length TRPV4 in the renal epithelial cells MDCK and its interaction with the transcriptional regulator β-catenin....
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