Gene-environment interactions increase the risk of pediatric-onset multiple sclerosis associated with ozone pollution.

doi:10.1177/13524585211069926

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Community

Back to search

Article

Gene-environment interactions increase the risk of pediatric-onset multiple sclerosis associated with ozone pollution.

Multiple sclerosis (Houndmills, Basingstoke, England) - 1 Aug 2022

Ziaei Amin, Lavery Amy M, Shao Xiaorong Ma, Adams Cameron, Casper T Charles, Rose John, Candee Meghan, Weinstock-Guttman Bianca, Aaen Greg, Harris Yolanda, Graves Jennifer, Benson Leslie, Gorman Mark, Rensel Mary, Mar Soe, Lotze Tim, Greenberg Benjamin, Chitnis Tanuja, Hart Janace, Waldman Amy T, Barcellos Lisa F, Waubant Emmanuelle

Abstract excerpt

BACKGROUND: We previously reported a relationship between air pollutants and increased risk of pediatric-onset multiple sclerosis (POMS). Ozone is an air pollutant that may play a role in multiple sclerosis (MS) pathoetiology. CD86 is the only non-HLA gene associated with POMS for which expression on antigen-presenting cells (APCs) is changed in response to ozone exposure. OBJECTIVES: To examine the association...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to B7-2 Antigen

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Child

Share to Gene-Environment Interaction

Share to Genetic Predisposition to Disease

Share to HLA-DRB1 Chains

Share to Multiple Sclerosis

Share to Ozone

Share to Risk Factors

Source

Open in PubMed Open full text

Identifiers

PMID: 35000467
DOI: 10.1177/13524585211069926
PMCID: PMC9256753

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 9 closest

Gene-environment interactions increase the risk of pediatric-onset multiple sclerosis associated with ozone pollution.PMID 35000467Read ↗

Gene–environment interactions: Epstein–Barr virus infection and risk of pediatric-onset multiple sclerosisSemantic proximity Read ↗

Genetic risk factors for pediatric-onset multiple sclerosis.Semantic proximity Read ↗

Gene-environment interactions increase the risk of paediatric-onset multiple sclerosis associated with household chemical exposures.Semantic proximity Read ↗

Genetic mechanisms of susceptibility to ozone-induced lung disease.Semantic proximity Read ↗

Identification of novel susceptibility genes in ozone-induced inflammation in mice.Semantic proximity Read ↗

Genetic susceptibility to ozone-induced lung inflammation in animal models of asthma.Semantic proximity Read ↗

Ambient ozone modifies the effect of tumor necrosis factor G-308A on bronchitic symptoms among children with asthma.Semantic proximity Read ↗

Association of tumor necrosis factor-alpha polymorphisms and ozone-induced change in lung function.Semantic proximity Read ↗

Associations of tumor necrosis factor G-308A with childhood asthma and wheezing.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.