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Article

Gene–environment interactions: Epstein–Barr virus infection and risk of pediatric-onset multiple sclerosis

9 Feb 2024

Abstract excerpt

Background and Objective: Prior Epstein–Barr virus (EBV) infection is associated with an increased risk of pediatric-onset multiple sclerosis (POMS) and adult-onset multiple sclerosis (MS). It has been challenging to elucidate the biological mechanisms underlying this association. We examined the interactions between candidate human leukocyte antigen (HLA) and non-HLA variants and childhood EBV infection as it...

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PMID: 38332747
DOI: 10.1177/13524585231224685

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