Article
COX-1, COX-2 and CYP2C19 variations may be related to cardiovascular events due to acetylsalicylic acid resistance.
Molecular biology reports - 1 Apr 2022
Kirac Deniz, Yaman Aysun Erdem, Doran Tansu, Mihmanli Mujgan, Keles Elif Cigdem
Abstract excerpt
BACKGROUND: In some stent implanted patients, cardiovascular events (CE) may occur. Acetylsalicylic acid (ASA) is routinely administered to these patients in order to prevent the occurrence of CE. CE may be related to gene variations which cause ASA resistance (AR). Therefore, it was aimed to investigate the relationship between COX-1, COX-2, CYP2C9 and CYP2C19 variations with CE due to AR. MATERIALS AND RESULTS:...
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