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Article

Effects of genetic factors to stent thrombosis due to clopidogrel resistance after coronary stent placement.

Cellular and molecular biology (Noisy-le-Grand, France) - 19 Jan 2016

Kirac D, Erdem A, Avcilar T, Yesilcimen K, Guney A I, Emre A, Yazici S, Terzi S, Kaspar E C, Cetin S E, Isbir T

Abstract excerpt

Stent thrombosis (ST) is considered as a multifactorial problem which is mostly occurs due to clopidogrel resistance. It may be due to some CYP450 enzyme deficiencies which play role in clopidogrel metabolism. Therefore the aim of this study is to detect the mutations in CYP2C19 and CYP2C9 genes which may cause ST, and to investigate the relation between other risk factors and ST. 50 individuals who have stent...

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PMID: 26828987

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