Article
Cancer worry among BRCA1/2 pathogenic variant carriers choosing surgery to prevent tubal/ovarian cancer: course over time and associated factors.
Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer - 1 Apr 2022
van Bommel Majke H D, Steenbeek Miranda P, IntHout Joanna, Hermens Rosella P M G, Hoogerbrugge Nicoline, Harmsen Marline G, van Doorn Helena C, Mourits Marian J E, van Beurden Marc, Zweemer Ronald P, Gaarenstroom Katja N, Slangen Brigitte F M, Brood-van Zanten Monique M A, Vos M Caroline, Piek Jurgen M, van Lonkhuijzen Luc R C W, Apperloo Mirjam J A, Coppus Sjors F P J, Prins Judith B, Custers José A E, de Hullu Joanne A
Abstract excerpt
OBJECTIVE: High cancer risks, as applicable to BRCA1 and BRCA2 pathogenic variant (PV) carriers, can induce significant cancer concerns. We examined the degree of cancer worry and the course of this worry among BRCA1/2-PV carriers undergoing surgery to prevent ovarian cancer, and identified factors associated with high cancer worry. METHODS: Cancer worry was evaluated as part of the multicentre, prospective...
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