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Article

Correlation between the risk of ovarian cancer and BRCA recurrent pathogenic variants in Japan.

Journal of human genetics - 1 May 2022

Sekine Masayuki, Enomoto Takayuki, Arai Masami, Yokoyama Shiro, Nomura Hiroyuki, Nishino Koji, Ikeuchi Takeshi, Kuriyama Yoko, Nakamura Seigo

Abstract excerpt

We previously reported that L63X and Q934X are BRCA1 common founder variants in Japan. So far, there have been no reports of a correlation between such BRCA common variants and the risk of BRCA-related cancers. In this analysis, we investigated the correlation between the risk of ovarian cancer (OC) and BRCA recurrent pathogenic variants. We examined the database of the Japanese organization of hereditary breast...

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Identifiers

PMID: 34983974
DOI: 10.1038/s10038-021-01002-z

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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