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Article

Clinicopathological Features of Patients with the BRCA1 c.5339T>C (p.Leu1780Pro) Variant.

Cancer research and treatment - 1 Jul 2020

Park Hyung Seok, Ryu Jai Min, Park Ji Soo, Im Seock-Ah, Jung So-Youn, Kim Eun-Kyu, Park Woo-Chan, Min Jun Won, Lee Jeeyeon, You Ji Young, Lee Jeong Eon, Kim Sung-Won

Abstract excerpt

PURPOSE: Recent studies revealed the BRCA1 c.5339T>C, p.Leu1780Pro variant (L1780P) is highly suggested as a likely pathogenic. The aim of this study was to evaluate clinicopathologic features of L1780P with breast cancer (BC) using multicenter data from Korea to reinforce the evidence as a pathogenic mutation and to compare L1780P and other BRCA1/2mutations using Korean Hereditary Breast Cancer (KOHBRA) study...

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Identifiers

PMID: 32019279
DOI: 10.4143/crt.2019.351
PMCID: PMC7373877

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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