Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Assessment of Association between miR-146a Polymorphisms and Expression of miR-146a, TRAF-6, and IRAK-1 Genes in Patients with Brucellosis.

Molecular biology reports - 1 Mar 2022

Kazemi Sima, Afshar Saeid, Keramat Fariba, Saidijam Massoud, Karami Manoochehr, Hashemi Seyed Hamid, Alikhani Mohammad Yousef

Abstract excerpt

BACKGROUND: Brucellosis is a major zoonosis all over the world. MicroRNAs are significant gene expression regulators and could be involved during the infections and also genetic alterations in the miRNAs sequence can affect primary miRNAs and precursor miRNAs processing and thus alter miRNAs expression. Current research studied the impact of the miR-146a polymorphism on miR-146a, TRAF-6, and IRAK-1 genes...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Brucellosis
Share to Case-Control Studies

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Interleukin-1 Receptor-Associated Kinases

Share to Intracellular Signaling Peptides and Proteins

Share to Leukocytes, Mononuclear

Share to MicroRNAs

Share to Polymorphism, Single Nucleotide

Share to Zoonoses

Source

Identifiers

PMID: 34981334
DOI: 10.1007/s11033-021-07014-4

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Assessment of Association between miR-146a Polymorphisms and Expression of miR-146a, TRAF-6, and IRAK-1 Genes in Patients with Brucellosis.PMID 34981334Read ↗

Association between risk of brucellosis and genetic variations in MicroRNA-146a.Semantic proximity Read ↗

The rs2910164 variant is associated with reduced miR-146a expression but not cytokine levels in patients with type 2 diabetes.Semantic proximity Read ↗

Correlations of miR-146a and IRAK1 gene polymorphisms with ankylosing spondylitis.Semantic proximity Read ↗

miR-146a polymorphism influences levels of miR-146a, IRAK-1, and TRAF-6 in young patients with coronary artery disease.Semantic proximity Read ↗

Significance of Polymorphism and Expression of miR-146a and NFkB1 Genetic Variants in Patients with Rheumatoid Arthritis.Semantic proximity Read ↗

Association between miRNA-146a and Polymorphisms of its Target Gene, IRAK1, Regarding Susceptibility to and Clinical Features of Systemic Lupus Erythematous and Multiple Sclerosis.Semantic proximity Read ↗

Dysregulation of miRNA-146a contributes to the development of lupus nephritis via targeting of TRAF6.Semantic proximity Read ↗

The functional polymorphisms of miR-146a are associated with susceptibility to severe sepsis in the Chinese population.Semantic proximity Read ↗

A polymorphism in the 3'-UTR of interleukin-1 receptor-associated kinase (IRAK1), a target gene of miR-146a, is associated with rheumatoid arthritis susceptibility.Semantic proximity Read ↗

Association of microRNA-146a and its target gene IRAK1 polymorphism with enthesitis related arthritis category of juvenile idiopathic arthritis.Semantic proximity Read ↗

Exploring the Associations and Molecular Impacts of miR-146a/rs2910164 and miR-196a2/rs185070757 with Rheumatoid Arthritis in a Pakistani Population.Semantic proximity Read ↗

Micro RNA-146a But Not IRAK1 is Associated with Rheumatoid Arthritis in the Tunisian Population.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.