Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Alteration in glycolytic/cholesterogenic gene expression is associated with bladder cancer prognosis and immune cell infiltration.

BMC cancer - 3 Jan 2022

Zhang Yuying, Zhu Baoyi, Cai Yi, Zhu Sihua, Zhao Hongjun, Ying Xiaoling, Jiang Chonghe, Zeng Jianwen

Abstract excerpt

BACKGROUND: Oncogenic metabolic reprogramming contributes to tumor growth and immune evasion. The intertumoral metabolic heterogeneity and interaction of distinct metabolic pathways may determine patient outcomes. In this study, we aim to determine the clinical and immunological significance of metabolic subtypes according to the expression levels of genes related to glycolysis and cholesterol-synthesis in...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Class I Phosphatidylinositol 3-Kinases
Share to Genomic Instability

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Glycolysis

Share to Immune System

Share to Lymphocytes, Tumor-Infiltrating

Share to Receptors, LDL

Share to Retinoblastoma Binding Proteins

Share to Tumor-Associated Macrophages

Source

Open in PubMed Open full text

Identifiers

PMID: 34980012
DOI: 10.1186/s12885-021-09064-0
PMCID: PMC8722165

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Alteration in glycolytic/cholesterogenic gene expression is associated with bladder cancer prognosis and immune cell infiltration.PMID 34980012Read ↗

Identification and Development of Subtypes With Poor Prognosis in Pan-Gynecological Cancer Based on Gene Expression in the Glycolysis-Cholesterol Synthesis AxisSemantic proximity Read ↗

Loss of the Y chromosome in bladder cancer drives metabolic reprogrammingSemantic proximity Read ↗

Altered gene expression in glycolysis-cholesterol synthesis axis correlates with outcome of triple-negative breast cancer.Semantic proximity Read ↗

Epigenetic dysregulation-induced metabolic reprogramming fuels tumor progression in bladder cancerSemantic proximity Read ↗

Epigenomic and Metabolomic Integration Reveals Dynamic Metabolic Regulation in Bladder CancerSemantic proximity Read ↗

Pathway-based cancer transcriptome deciphers a high-resolution intrinsic heterogeneity within bladder cancer classificationSemantic proximity Read ↗

Identification of Metabolic Reprogramming Related Gene Signature to Predict the Prognosis of Bladder Cancer PatientsSemantic proximity Read ↗

Integrated spatial transcriptome and metabolism study reveals metabolic heterogeneity in human bladder cancerSemantic proximity Read ↗

Construction and Validation of a Prognostic Model of Metabolism-Related Genes Driven by Somatic Mutation in Bladder Cancer.Semantic proximity Read ↗

Metabolic‐associated signature and hub genes associated with immune microenvironment and prognosis in bladder cancerSemantic proximity Read ↗

Metabolic-Associated Signature and Hub Genes Associated with Immune Microenvironment and Prognosis in Bladder CancerSemantic proximity Read ↗

Prognosis analysis and validation of lipid metabolism-associated lncRNAs and tumor immune microenvironment in bladder cancerSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.