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Article

VDR Polymorphisms in Autoimmune Connective Tissue Diseases: Focus on Italian Population.

Journal of immunology research - 1 Jan 2021

Latini Andrea, De Benedittis Giada, Perricone Carlo, Colafrancesco Serena, Conigliaro Paola, Ceccarelli Fulvia, Chimenti Maria Sole, Novelli Lucia, Priori Roberta, Conti Fabrizio, Ciccacci Cinzia, Borgiani Paola

Abstract excerpt

Vitamin D is an important hormone involved in various physiologic processes, and its activity is linked to binding with vitamin D receptor (VDR). Genetic polymorphisms in the VDR gene could modulate the expression or function of the receptor and, consequently, alter the effects of vitamin D. Variants in VDR gene have been associated with susceptibility to many illnesses sensitive to vitamin D administration and...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 34977255
DOI: 10.1155/2021/5812136
PMCID: PMC8718283

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