Article
Elucidating the Role of Vitamin D Receptor (VDR) Polymorphisms in Genetic Susceptibility to Systemic Lupus Erythematosus: A Case-Control Study From Western India.
International journal of immunogenetics - 1 Apr 2026
Pawaskar Swapnal, Chougule Durga, Jose Amrutha, Rajadhyaksha Anjali, Nadkar Milind, Sawardekar Riddhi, Rai Kirti, Kharkar Harshada, Madkaikar Manisha, Pradhan Vandana D
Abstract excerpt
Systemic lupus erythematosus (SLE) is a heterogeneous autoimmune disorder influenced by genetic and environmental factors. Vitamin D deficiency and vitamin D receptor (VDR) gene polymorphisms are suggested to modulate immune dysregulation in SLE. This study aimed to investigate the association of VDR polymorphisms (BsmI, ApaI, TaqI and FokI), serum 25-hydroxyvitamin D [25-OH vitamin D] levels and clinical...
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