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Mitochondrial Genome Study Identifies Association Between Primary Open-Angle Glaucoma and Variants in MT-CYB, MT-ND4 Genes and Haplogroups

16 Dec 2021

Abstract excerpt

Background and purpose: Primary open-angle glaucoma (POAG) is an optic neuropathy characterized by death of retinal ganglion cells and atrophy of the optic nerve head. The susceptibility of the optic nerve to damage has been shown to be mediated by mitochondrial dysfunction. In this study, we aimed to determine a possible association between mitochondrial SNPs or haplogroups and POAG. Methods: Mitochondrial DNA...

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Identifiers

PMID: 34976016
DOI: 10.3389/fgene.2021.781189

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 3 Sept 2026.

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