Article
The role of mitochondrial haplogroups in primary open angle glaucoma.
The British journal of ophthalmology - 1 Apr 2006
Andrews R, Ressiniotis T, Turnbull D M, Birch M, Keers S, Chinnery P F, Griffiths P G
Abstract excerpt
AIM: To investigate a possible association between mitochondrial haplogroups and primary open angle glaucoma (POAG). METHODS: Genomic DNA was extracted from 140 POAG patients and 75 healthy individuals. Restriction enzyme digest analysis of polymerase chain reaction (PCR) amplified fragments was used to determine the mitochondrial haplogroup of each patient and control. RESULTS: The median age was 73 years for...
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