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Article

Mitochondrial DNA variant discovery in normal-tension glaucoma patients by next-generation sequencing.

Investigative ophthalmology & visual science - 24 Feb 2014

Jeoung Jin Wook, Seong Moon-Woo, Park Sung Sup, Kim Dong Myung, Kim Seok Hwan, Park Ki Ho

Abstract excerpt

PURPOSE: Normal-tension glaucoma (NTG) is a disease of late onset, complex trait with multiple risk factors. In this study, we discovered a mitochondrial DNA variant in NTG patients using next-generation sequencing (NGS). METHODS: The DNA was extracted from the peripheral blood of NTG patients and normal control subjects. Sequencing of the entire mitochondrial DNA (mtDNA) using NGS revealed new genetic risk...

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Share to DNA, Mitochondrial
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 24448266
DOI: 10.1167/iovs.13-12968

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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