Article
A frameshift deletion in the GDF9 gene in Icelandic Loa prolific sheep.
Animal genetics - 1 Apr 2022
Holm Lars-Erik, Bendixen Christian, Eythorsdottir Emma, Hallsson Jon H
Abstract excerpt
Several genetic variants have been shown to affect the mean number of offspring in different sheep breeds. Here, we analyzed samples from Icelandic sheep with the aim of identifying the genetic cause of the Icelandic Loa phenotype using three previously identified prolificacy genes as candidates. We demonstrate that a 4-bp frameshift deletion positioned in the mature region of the GDF9 protein in the Loa animals...
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