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A missense mutation in growth differentiation factor 9 (GDF9) is strongly associated with litter size in sheep.

BMC genetics - 2 Jan 2013

Våge Dag I, Husdal Maren, Kent Matthew P, Klemetsdal Gunnar, Boman Inger A

Abstract excerpt

BACKGROUND: A genome wide association study for litter size in Norwegian White Sheep (NWS) was conducted using the recently developed ovine 50K SNP chip from Illumina. After genotyping 378 progeny tested artificial insemination (AI) rams, a GWAS analysis was performed on estimated breeding values (EBVs) for litter size. RESULTS: A QTL-region was identified on sheep chromosome 5, close to the growth...

Topics

Animals
Female
Gene Frequency
Genome-Wide Association Study
Growth Differentiation Factor 9
Litter Size
Mutation, Missense
Polymorphism, Single Nucleotide
Sheep

Source

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Open in PubMed Open full text

Identifiers

PMID: 23280002
DOI: 10.1186/1471-2156-14-1
PMCID: PMC3546915

Genes

GDF9

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

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