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Article

Direct evidence on the contribution of a missense mutation in GDF9 to variation in ovulation rate of Finnsheep.

PloS one - 1 Jan 2014

Mullen Michael P, Hanrahan James P

Abstract excerpt

The Finnish Landrace (Finnsheep) is a well known high-prolificacy sheep breed and has been used in many countries as a source of genetic material to increase fecundity of local breeds. Analyses to date have indicated that mutations with a large effect on ovulation rate are not responsible for the exceptional prolificacy of Finnsheep. The objectives of this study were to ascertain if: 1) any of 12 known mutations...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 24751660
DOI: 10.1371/journal.pone.0095251
PMCID: PMC3994038

Genes

GDF9
BMP15

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Direct evidence on the contribution of a missense mutation in GDF9 to variation in ovulation rate of Finnsheep.PMID 24751660Read ↗

Homozygosity for a single base-pair mutation in the oocyte-specific GDF9 gene results in sterility in Thoka sheep.Semantic proximity Read ↗

Mutation in the protease cleavage site of GDF9 increases ovulation rate and litter size in heterozygous ewes and causes infertility in homozygous ewes.Semantic proximity Read ↗

Investigation of prolific sheep from UK and Ireland for evidence on origin of the mutations in BMP15 (FecX(G), FecX(B)) and GDF9 (FecG(H)) in Belclare and Cambridge sheep.Semantic proximity Read ↗

Screening for Causative Mutations of Major Prolificacy Genes in Iranian Fat-Tailed Sheep.Semantic proximity Read ↗

Mutations in the genes for oocyte-derived growth factors GDF9 and BMP15 are associated with both increased ovulation rate and sterility in Cambridge and Belclare sheep (Ovis aries).Semantic proximity Read ↗

Genome-wide identification of a regulatory mutation in <i>BMP15</i> controlling prolificacy in sheepSemantic proximity Read ↗

A missense mutation in growth differentiation factor 9 (GDF9) is strongly associated with litter size in sheep.Semantic proximity Read ↗

A frameshift deletion in the GDF9 gene in Icelandic Loa prolific sheep.Semantic proximity Read ↗

Major genes affecting ovulation rate in sheep.Semantic proximity Read ↗

Polymorphisms in GDF9 and BMP15 associated with fertility and ovulation rate in Moghani and Ghezel sheep in Iran.Semantic proximity Read ↗

Genetic mutations influencing ovulation rate in sheep.Semantic proximity Read ↗

Polymorphism study of growth differentiation factor 9B (GDF9B) gene and its association with reproductive traits in sheep.Semantic proximity Read ↗

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