Article
Elevated serum expression of p53 and association of TP53 codon 72 polymorphisms with risk of cervical cancer in Bangladeshi women.
PloS one - 1 Jan 2021
Mostaid Md Shaki, Mumu Sadia Biswas, Haque Md Aminul, Sharmin Shahana, Jamiruddin Mohd Raeed, Sayedur Rahman Ghazi Muhammad, Reza Hasan Mahmud
Abstract excerpt
Differential expression of p53 has been reported in cervical cancer, primarily in tumor tissue biopsies. In this study, we examined the association of TP53 codon 47 and codon 72 polymorphisms and serum level expression of p53 in cervical cancer patients (n = 129) and healthy controls (n = 122). We found elevated levels of serum p53 protein levels in cervical cancer patients (p = 0.0442) compared to healthy...
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