Article
TP53 genetic polymorphisms and susceptibility to cervical cancer in Bangladeshi women: a case-control study.
Molecular biology reports - 1 Jun 2020
Apu Mohd Nazmul Hasan, Rashed A Z M, Bashar Tafsir, Rahman Md Morshadur, Mostaid Md Shaki
Abstract excerpt
Pharmacogenetic study of TP53 gene polymorphisms has not been conducted extensively in cervical cancer. The aim of this study was to assesses the TP53 codon 72 and codon 47 polymorphisms and their relation to cervical cancer risk in Bangladeshi women. 134 cervical cancer patients and 102 age matched healthy controls were included from two institutions in Bangladesh. Polymerase chain reaction-restriction fragment...
Topics
- Adult
- Alleles
- Bangladesh
- Case-Control Studies
- Codon
- Disease Susceptibility
- Ethnicity
- Female
- Gene Frequency
- Genes, p53
- Genetic Predisposition to Disease
- Genotype
- Humans
- Middle Aged
- Polymorphism, Single Nucleotide
- Risk Factors
- Tumor Suppressor Protein p53
- Uterine Cervical Neoplasms