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Article

Development of hepatocellular carcinoma from various phases of chronic hepatitis B virus infection.

PloS one - 1 Jan 2021

Suzuki Takanori, Matsuura Kentaro, Nagura Yoshihito, Iio Etsuko, Ogawa Shintaro, Fujiwara Kei, Nojiri Shunsuke, Kataoka Hiromi, Tanaka Yasuhito

Abstract excerpt

BACKGROUND & AIMS: There is insufficient data on the clinical course of chronic hepatitis B (CHB) patients in the immune-tolerant (IT) and immune-clearance, inactive (IC) phases over a long follow-up period. DESIGN: We enrolled 466 CHB patients from our historical cohort, including 56 IT+MA　 (mildly active), 134 IC, 230 with chronic active hepatitis (CH) and 46 with liver cirrhosis (LC), who were categorized to...

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Source

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Identifiers

PMID: 34962955
DOI: 10.1371/journal.pone.0261878
PMCID: PMC8714106

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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