Article
The natural history of chronic HBV infection and geographical differences.
Antiviral therapy - 1 Jan 2010
Liaw Yun-Fan, Brunetto Maurizia R, Hadziyannis Stephanos
Abstract excerpt
Although chronic HBV infection is a global health issue, there are geographical differences in the mode of transmission, prevalence and HBV genotype distribution. Chronic HBV infection is a dynamic state of interactions between HBV, hepatocytes and immune cells of the host. Accordingly, the natural history of chronic HBV infection typically starts with an immune tolerant phase, followed by an immune clearance...
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