Natural history of chronic hepatitis B: special emphasis on disease progression and prognostic factors.

doi:10.1016/j.jhep.2007.11.011

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Article

Natural history of chronic hepatitis B: special emphasis on disease progression and prognostic factors.

Journal of hepatology - 1 Feb 2008

Fattovich Giovanna, Bortolotti Flavia, Donato Francesco

Abstract excerpt

The natural history of chronic hepatitis B virus (HBV) infection and disease is complex and highly variable. We review the natural history of chronic hepatitis B with emphasis on the rates of disease progression and factors influencing the course of the liver disease. Chronic hepatitis B is characterized by an early replicative phase (HBeAg positive chronic hepatitis) and a late low or non-replication phase with...

Topics

Carcinoma, Hepatocellular
Disease Progression
Genotype
Hepatitis B Surface Antigens
Hepatitis B e Antigens
Hepatitis B virus
Hepatitis B, Chronic
Humans
Liver Cirrhosis
Liver Neoplasms
Mutation
Prognosis
Virus Replication

Source

Open in PubMed

Identifiers

PMID: 18096267
DOI: 10.1016/j.jhep.2007.11.011

Provenance

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