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Article

Diagnostic accuracy of 1p/19q codeletion tests in oligodendroglioma: A comprehensive meta-analysis based on a Cochrane systematic review.

Neuropathology and applied neurobiology - 1 Jun 2022

Brandner Sebastian, McAleenan Alexandra, Jones Hayley E, Kernohan Ashleigh, Robinson Tomos, Schmidt Lena, Dawson Sarah, Kelly Claire, Leal Emmelyn Spencer, Faulkner Claire L, Palmer Abigail, Wragg Christopher, Jefferies Sarah, Vale Luke, Higgins Julian P T, Kurian Kathreena M

Abstract excerpt

Codeletion of chromosomal arms 1p and 19q, in conjunction with a mutation in the isocitrate dehydrogenase 1 or 2 gene, is the molecular diagnostic criterion for oligodendroglioma, IDH mutant and 1p/19q codeleted. 1p/19q codeletion is a diagnostic marker and allows prognostication and prediction of the best drug response within IDH-mutant tumours. We performed a Cochrane review and simple economic analysis to...

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Identifiers

PMID: 34958131
DOI: 10.1111/nan.12790
PMCID: PMC9208578

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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