Article
MRI and CT Identify Isocitrate Dehydrogenase (IDH)-Mutant Lower-Grade Gliomas Misclassified to 1p/19q Codeletion Status with Fluorescence in Situ Hybridization.
Radiology - 1 Jan 2020
Patel Sohil H, Batchala Prem P, Mrachek E Kelly S, Lopes Maria-Beatriz S, Schiff David, Fadul Camilo E, Patrie James T, Jain Rajan, Druzgal T Jason, Williams Eli S
Abstract excerpt
Background Fluorescence in situ hybridization (FISH) is a standard method for 1p/19q codeletion testing in diffuse gliomas but occasionally renders erroneous results. Purpose To determine whether MRI/CT analysis identifies isocitrate dehydrogenase (IDH)-mutant gliomas misassigned to 1p/19q codeletion status with FISH. Materials and Methods Data in patients with IDH-mutant lower-grade gliomas (World Health...
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