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Article

Association of miR-21 and miR-335 to microsatellite instability and prognosis in stage III colorectal cancer.

Cancer biomarkers : section A of Disease markers - 1 Jan 2022

Calvo-López Tania, Paz-Cabezas Mateo, Llovet Patricia, Ibañez Maria Dolores, Sastre Javier, Alonso-Orduña Vicente, Viéitez J Ma, Yubero Alfonso, Vera Ruth, Asensio-Martínez Elena, Garcia-Alfonso Pilar, Aranda Enrique, Diaz-Rubio Eduardo, Perez-Villamil Beatriz

Abstract excerpt

BACKGROUND: MicroRNAs (miRs) are frequently altered in colorectal cancer (CRC) and can be used as prognostic factors. OBJECTIVE: To confirm in stage III CRC patients a reported miR signature that was associated to the presence of metastatic disease. To correlate miR expression with microsatellite instability (MSI) and mutations in RAS and BRAF. METHODS: miR-21, miR-135a, miR-206, miR-335 and miR-Let-7a expression...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Proto-Oncogene Proteins B-raf

Source

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Identifiers

PMID: 34958006
DOI: 10.3233/CBM-210353
PMCID: PMC12364284

Genes

BRAF

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026.

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