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Article

microRNA-193a-3p is specifically down-regulated and acts as a tumor suppressor in BRAF-mutated colorectal cancer.

BMC cancer - 7 Nov 2017

Takahashi Hidekazu, Takahashi Masanobu, Ohnuma Shinobu, Unno Michiaki, Yoshino Yuki, Ouchi Kota, Takahashi Shin, Yamada Yasuhide, Shimodaira Hideki, Ishioka Chikashi

Abstract excerpt

BACKGROUND: The aim of this study was to identify miRNAs specifically dysregulated in BRAF-mutated colorectal cancer, which could lead to a better understanding of the molecular mechanisms underlying oncogenesis of this malignant subtype of colorectal cancer. METHODS: Candidate dysregulated miRNAs were selected in genome-wide miRNA expression array analysis using a screening set composed of 15 BRAF-mutated and 15...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Colorectal Neoplasms

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Share to Gene Expression Regulation, Neoplastic

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Share to Proto-Oncogene Proteins B-raf

Source

Open in PubMed Open full text

Identifiers

PMID: 29115941
DOI: 10.1186/s12885-017-3739-x
PMCID: PMC5678600

Genes

BRAF
EGFR
KRAS

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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