Article
The corona of protein-gold nanoparticle systems: the role of ionic strength.
Physical chemistry chemical physics : PCCP - 19 Jan 2022
Cantarutti Cristina, Hunashal Yamanappa, La Rosa Carmelo, Condorelli Marcello, Giorgetti Sofia, Bellotti Vittorio, Fogolari Federico, Esposito Gennaro
Abstract excerpt
The nature of the nanoparticle-protein corona is emerging as a key aspect in determining the impact of nanomaterials on proteins and in general on the biological response. We previously demonstrated that citrate-stabilized gold nanoparticles (Cit-AuNPs) interact with β2-microglobulin (β2m) preserving the protein native structure. Moreover, Cit-AuNPs are able to hinder in vitro fibrillogenesis of a β2m pathologic...
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