Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Gcn5 determines the fate of Drosophila germline stem cells through degradation of Cyclin A.

FASEB journal : official publication of the Federation of American Societies for Experimental Biology - 1 May 2017

Liu Tianqi, Wang Qi, Li Wenqing, Mao Feiyu, Yue Shanshan, Liu Sun, Liu Xiaona, Xiao Shan, Xia Laixin

Abstract excerpt

The fluctuating CDK-CYCLIN complex plays a general role in cell-cycle control. Many types of stem cells use unique features of the cell cycle to facilitate asymmetric division. However, the manner in which these features are established remains poorly understood. The cell cycle of Drosophila female germline stem cells (GSCs) is characterized by short G1 and very long G2 phases, making it an excellent model for...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cell Cycle
Share to Cyclin A

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Drosophila melanogaster

Share to Drosophila Proteins

Share to Germ Cells

Share to Histone Acetyltransferases

Share to Stem Cells

Source

Identifiers

PMID: 28188175
DOI: 10.1096/fj.201601217R

Genes

GSC

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Gcn5 determines the fate of Drosophila germline stem cells through degradation of Cyclin A.PMID 28188175Read ↗

Cyclin E controls Drosophila female germline stem cell maintenance independently of its role in proliferation by modulating responsiveness to niche signals.Semantic proximity Read ↗

Whole-animal genome-wide RNAi screen identifies networks regulating male germline stem cells in Drosophila.Semantic proximity Read ↗

Effete-mediated degradation of Cyclin A is essential for the maintenance of germline stem cells in Drosophila.Semantic proximity Read ↗

Cyclin E and Cdk2 Control GLD-1, the Mitosis/Meiosis Decision, and Germline Stem Cells in Caenorhabditis elegansSemantic proximity Read ↗

GCN5: a supervisor in all-inclusive control of vertebrate cell cycle progression through transcription regulation of various cell cycle-related genes.Semantic proximity Read ↗

The <i>Drosophila</i> histone methyl-transferase SET1 coordinates multiple signaling pathways in regulating male germline stem cell maintenance and differentiationSemantic proximity Read ↗

Asymmetric distribution of centromere proteins between germline stem and daughter cells maintains a balanced niche in Drosophila malesSemantic proximity Read ↗

Epigenetic regulation of stem cell maintenance in the Drosophila testis via the nucleosome-remodeling factor NURF.Semantic proximity Read ↗

Chromatin and gene expression changes during female Drosophila germline stem cell development illuminate the biology of highly potent stem cellsSemantic proximity Read ↗

Cyclin A2 is essential for mouse gonocyte maturation.Semantic proximity Read ↗

Differential condensation of sister chromatids coordinates with Cdc6 to ensure distinct cell cycle progression in <i>Drosophila</i> male germline stem cell lineageSemantic proximity Read ↗

The COP9 signalosome promotes degradation of Cyclin E during early Drosophila oogenesis.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.